Endocrine Abstracts

Introduction: Immune-checkpoint inhibitors are used in patients with advanced cancers. They are associated with a wide array of side effects known as immune-related adverse events (irAEs). These can affect skin, gastrointestinal tract, multiple endocrine glands, liver and other systems. We report a 69-year-old male with a past medical history of Chronic Obstructive Pulmonary Disease and Lung cancer who was referred by the oncology team with a clinical and biochemical picture o...

Background: HDR syndrome also known by the eponym Barakat syndrome, is a rare, autosomal dominant disorder characterized by the triad of hypoparathyroidism, sensorineural hearing loss, and renal abnormalities. It is caused due to mutation (haploinsufficiency) in GATA3 gene on chromosome 10p with a wide spectrum of phenotypic variations.Case Presentation: A 33-year-old lady presented to emergency department with an episod...

Background: Duchenne muscular dystrophy (DMD) is a progressive muscle disorder characterised by muscle wasting and weakness. It is often associated with intracellular hypercalcaemia in dystrophin deficient muscle leading to disease progression. We present a comprehensive case report of extracellular hypercalcaemia in a DMD patient, a rare complication, emphasising the interplay of iatrogenic factors, immobilisation, and therapeutic approaches.<p class="abs...